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Amyotrophic lateral sclerosis diagnosis and differential

作者:Admin时间:08-05-23 点击:

First, medical history and symptoms:

1.40 over the age of many of the older, male to female ratio of about 3:2, the slow onset, sexual development.

2. Around the upper limbs to paralysis, the paralysis of the lower limbs hub, from top to bottom mixed motor neuron damage to both the symptoms characteristic.

3. Palsy symptoms, cranial nerve damage after the group appeared unclear articulation, swallowing difficulties, such as drinking water choking.

4. Have no sense of obstacles.

Second, the medical examination found that:

Cranial nerve: In addition palsy, may have Sheji atrophy, Sheji defibrillators, strong cry-laugh, emotional instability, and so on.多见remote-based upper limb muscle atrophy to the size of fish muscle, bone between the muscle for a while with muscle bundle fibrillation, I feel normal. Both lower limbs were spastic paralysis, muscle tension increased tendon hyperreflexia, reflecting the positive bilateral pathology. Respiratory muscles are involved in breathing difficulties.

Third, support check:

1. Lumbar puncture CSF examination: more than normal pressure and composition.

2. Serum CPK can be increased, increased acetylcholinesterase.

3. EMG: visible fibrillation potential, great potential, motor nerve conduction velocity more than normal.

4.MRI: Clinical and visible damage to the corresponding parts of the spinal muscular atrophy degeneration, and so on.

4, identification:

Sometimes required and cervical disease, high cervical cancer, spinal cord Yandeng identification.


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