The main performance
This is a disease of young adults during the central nervous system demyelinating disease. In the age of onset between 20-40 years old, the peak incidence for the 30-year-old, slightly more female, male to female ratio is 1:1.2. Cause may be related to genetic factors, viral infections, immune response, the environment and other relevant factors. For a sub-acute onset, characterized by multiple lesions, clinical performance variability, disease and more volatile, often with ease recurrence. Symptoms can be the precursor for the arm weakness, difficulty swallowing pronunciation, leg weakness or the aforementioned joint symptoms, but usually the way for the hand and arm the weak symmetry, fine motor difficulties, and gradually appear muscular atrophy, inter-muscular bones, muscles and earthworm-shaped Fish muscle early involvement, and adjacent to the spread of the proximal muscles. Involvement in the lower limbs and upper limbs simultaneously, or after. She Ji, orbicularis oris muscle, muscular atrophy inability to chew slowly, and pronunciation difficulties arising from swallowing, choking or drooling, muscle bundle tremor widely seen in the limbs, trunk, mouth, face and other parts, from time to time arise. Pyramidal tract symptoms and muscular atrophy, muscle bundle tremor, and other symptoms of motor neuron coexistence, limbs tendon hyperreflexia and a pathological reflection. Sometimes upper tendon reflexes weakened or disappeared, and lower extremities hyperreflexia, cramps. Sphincter and sexual dysfunction is not common, have no objective obstacles to the feeling. Most patients died two to five years to the medullary symptom onset or mainly to a shorter survival time.
Ocular involvement in general do not feel normal. Nerve function almost always normal. Urine and sexual function is generally not involved. Serious denervation of muscle stretch reflex has weakened, but often the inability of motor neuron tendon reflexes active with the ALS patients, it is almost a characteristic line can see, often Babinski levy.
According to lesions of different parts, that the following symptoms:
1, easily agitated mood, or see strong cry-laugh, and memory diminish, or lack of awareness of intellectual decline, to be advanced dementia.
2, due to language barriers and more cerebellar lesions or pseudobulbar palsy, that unclear articulation, voice, varying severity, and even vocal cord paralysis.
3, cranial nerve dysfunction caused by optic neuritis that the vision loss, dark vision center point. Inter-nuclear ophthalmoplegia, diplopia, blepharoptosis, irregular or narrow the pupil, are also common, such as nystagmus performance. 1-2% of patients have trigeminal neuralgia, and some can be met paralysis, facial spasm, and so on.
4, sensory dysfunction is often caused by spinal cord lesions. Common flu symptoms acupuncture, numbness, but also a sense of banding, burning sensation, cold or flu feel extremely painful. Common pain in the back, legs and upper small.
5, movement disorders, including spastic paralysis, cerebellar ataxia. Early that clumsy hand movements and tremor, or lower limbs, and so easy to trip. Or see speech dysarthria and pain of ankylosing muscle spasm.
6, Other Diseases. A small number of patients with early onset frequency, urgency, the latter part of a urine retention or incontinence. Some patients have decreased sexual desire and impotence. There is no specific modern medical treatments. Can be applied, such as hormone and immune inhibitors. Upper respiratory tract infection, surgery, trauma, other infectious diseases, Shouhan, maternity, mental stimulation, overworked, and other factors, the disease is likely to trigger factors.
Early features
Fatigue, muscle weakness, especially on the distal lower limb muscle, muscle bundle tremors, loss of muscle volume and strength diminish. Dysarthria, no callback (breathlessness) is a rare performance of the disease. Feeling of performance, a hand acupuncture flu (pins and needness in the hands) to this nerve and loss of control of the process is accompanied by the early characteristics of the disease.
This is a disease of young adults during the central nervous system demyelinating disease. In the age of onset between 20-40 years old, the peak incidence for the 30-year-old, slightly more female, male to female ratio is 1:1.2. Cause may be related to genetic factors, viral infections, immune response, the environment and other relevant factors. For a sub-acute onset, characterized by multiple lesions, clinical performance variability, disease and more volatile, often with ease recurrence. Symptoms can be the precursor for the arm weakness, difficulty swallowing pronunciation, leg weakness or the aforementioned joint symptoms, but usually the way for the hand and arm the weak symmetry, fine motor difficulties, and gradually appear muscular atrophy, inter-muscular bones, muscles and earthworm-shaped Fish muscle early involvement, and adjacent to the spread of the proximal muscles. Involvement in the lower limbs and upper limbs simultaneously, or after. She Ji, orbicularis oris muscle, muscular atrophy inability to chew slowly, and pronunciation difficulties arising from swallowing, choking or drooling, muscle bundle tremor widely seen in the limbs, trunk, mouth, face and other parts, from time to time arise. Pyramidal tract symptoms and muscular atrophy, muscle bundle tremor, and other symptoms of motor neuron coexistence, limbs tendon hyperreflexia and a pathological reflection. Sometimes upper tendon reflexes weakened or disappeared, and lower extremities hyperreflexia, cramps. Sphincter and sexual dysfunction is not common, have no objective obstacles to the feeling. Most patients died two to five years to the medullary symptom onset or mainly to a shorter survival time.
Ocular involvement in general do not feel normal. Nerve function almost always normal. Urine and sexual function is generally not involved. Serious denervation of muscle stretch reflex has weakened, but often the inability of motor neuron tendon reflexes active with the ALS patients, it is almost a characteristic line can see, often Babinski levy.
According to lesions of different parts, that the following symptoms:
1, easily agitated mood, or see strong cry-laugh, and memory diminish, or lack of awareness of intellectual decline, to be advanced dementia.
2, due to language barriers and more cerebellar lesions or pseudobulbar palsy, that unclear articulation, voice, varying severity, and even vocal cord paralysis.
3, cranial nerve dysfunction caused by optic neuritis that the vision loss, dark vision center point. Inter-nuclear ophthalmoplegia, diplopia, blepharoptosis, irregular or narrow the pupil, are also common, such as nystagmus performance. 1-2% of patients have trigeminal neuralgia, and some can be met paralysis, facial spasm, and so on.
4, sensory dysfunction is often caused by spinal cord lesions. Common flu symptoms acupuncture, numbness, but also a sense of banding, burning sensation, cold or flu feel extremely painful. Common pain in the back, legs and upper small.
5, movement disorders, including spastic paralysis, cerebellar ataxia. Early that clumsy hand movements and tremor, or lower limbs, and so easy to trip. Or see speech dysarthria and pain of ankylosing muscle spasm.
6, Other Diseases. A small number of patients with early onset frequency, urgency, the latter part of a urine retention or incontinence. Some patients have decreased sexual desire and impotence. There is no specific modern medical treatments. Can be applied, such as hormone and immune inhibitors. Upper respiratory tract infection, surgery, trauma, other infectious diseases, Shouhan, maternity, mental stimulation, overworked, and other factors, the disease is likely to trigger factors.
Early features
Fatigue, muscle weakness, especially on the distal lower limb muscle, muscle bundle tremors, loss of muscle volume and strength diminish. Dysarthria, no callback (breathlessness) is a rare performance of the disease. Feeling of performance, a hand acupuncture flu (pins and needness in the hands) to this nerve and loss of control of the process is accompanied by the early characteristics of the disease.
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